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AVN-944

Catalogue number:
HY-13560-5mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

297730-17-7

Purity:

99.89

Molecular Formula:

C25H27N5O5

Molecular Weight:

477.51

Mass Spectrometry:

Reference Materials

Alternative Names:

VX-944

Product Description:

AVN-944 (VX-944) is an orally active, potent, selective, noncompetitive and specific inhibitor of IMPDH (inosine monophosphate dehydrogenase). AVN-944 is an essential rate-limiting enzyme in de novo guanine nucleotide synthesis. AVN-944 is also an inhibitor of arenavirus RNA synthesis, and blocks arenavirus infection. AVN-944 has broad anti-cancer activities, and can be used for multiple myeloma (MM) and acute myeloid leukemia (AML) research[1][2][3].