AZD3839 (free base)
Catalogue number:
HY-13438-10mg
Supplier:
Size:
10 mg
Product is available in:
£244.00
Special price until 31 Dec 2025
Normal price £271.00
Shipping is calculated in checkout
Normal price £271.00
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1227163-84-9
Purity:
99.98
Molecular Formula:
C24H16F3N5
Molecular Weight:
431.41
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- MSDS: View or download
- Protocol: View or download
Product Description:
AZD3839 free base is a potent and selective orally active, brain-permeable BACE1 inhibitor (Ki=26 nM). AZD3839 free base shows 14 and >1000-fold selectivity against BACE2 and cathepsin D, respectively. AZD3839 free base exhibits dose- and time-dependent lowering of plasma, brain, and cerebrospinal fluid Aβ levels in mouse, guinea pig, and non-human primate. AZD3839 free base can be used for the research of Alzheimer's disease[1][2].