Adagrasib
Catalogue number:
HY-130149-500mg
Supplier:
Size:
500 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2326521-71-3
Purity:
99.79
Molecular Formula:
C32H35ClFN7O2
Molecular Weight:
604.12
Mass Spectrometry:
Reference Materials
Alternative Names:
MRTX849
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Adagrasib (MRTX849) is a potent, orally-available, and mutation-selective covalent inhibitor of KRAS G12C with potential antineoplastic activity. Adagrasib covalently binds to KRAS G12C at the cysteine at residue 12, locks the protein in its inactive GDP-bound conformation, and inhibits KRAS-dependent signal transduction[1][2].