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JBSNF-000088

Catalogue number:
HY-112584-100mg
Supplier:
Size:
100 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

7150-23-4

Purity:

99.94

Molecular Formula:

C7H8N2O2

Molecular Weight:

152.15

Mass Spectrometry:

Reference Materials

Alternative Names:

6-Methoxynicotinamide

Product Description:

JBSNF-000088 (6-Methoxynicotinamide), a analog of nicotinamide (NA), is a potent and orally active Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 µM, 2.8 µM, and 5.0 µM for human NNMT, monkey NNMT and mouse NNMT, respectively. JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization, glucose modulation and body weight reduction in animal models of metabolic disease[1].