TAK-243
Catalogue number:
HY-100487-1mL
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1450833-55-2
Purity:
98.38
Molecular Formula:
C19H20F3N5O5S2
Molecular Weight:
519.52
Mass Spectrometry:
Reference Materials
Alternative Names:
MLN7243
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. TAK-243 (MLN7243) induces endoplasmic reticulum (ER) stress, abrogates NF-κB pathway activation and promotes apoptosis[1][2]. 10mM