Herpesvirus 8 Monoclonal Antibody
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Immunohistochemistry
Rat
Herpesvirus
CCS
Monoclonal
Anti-Herpesvirus 8 Antibody was produced in rats by repeated immunizations with recombinant protein corresponding to the latent nuclear antigen-1 mole
Herpes, Herpesvirus, HHV8, latent nuclear antigen, LNA, viral gene orf 73
HHV 8 encodes a latent nuclear antigen (LNA) , which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposi’s sarcoma. Anti-Herpesvirus 8 (RAT) Monoclonal Antibody was tested in IHC-P with positive control Karposi sarcoma tissues. Cellular Localization: Nuclear. The user is advised to validate the use of the products with their tissue specimens prepared and handled in accordance with their laboratory practices. Consult references (Kiernan, 1981: Sheehan & Hrapchak, 1980) for further details on specimen preparation.
Store at 2 - 8°C. This antibody is suitable for use until the expiration date when stored at 2 - 8°C