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N3-C5-NHS ester

Catalogue number:
HY-126523-500mg
Supplier:
Size:
500 mg
£1714.00
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This product is no longer available to order.
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

866363-70-4

Purity:

98.04

Molecular Formula:

C10H14N4O4

Molecular Weight:

254.24

Product Description:

N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-C5-NHS ester is a click chemistry reagent, itcontains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.