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Azido-PEG6-NHS ester

Catalogue number:
HY-130474-100mg
Supplier:
Size:
100 mg
Product is available in:
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£218.00 Special price until 31 Dec 2025
Normal price £242.00
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2055014-64-5

Purity:

98.85

Molecular Formula:

C19H32N4O10

Molecular Weight:

476.48

Product Description:

Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG6-NHS ester is a click chemistry reagent, itcontains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.