Azido-PEG6-NHS ester
Catalogue number:
HY-130474-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2055014-64-5
Purity:
98.85
Molecular Formula:
C19H32N4O10
Molecular Weight:
476.48
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- Protocol: View or download
Product Description:
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG6-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.