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Zabedosertib

Catalogue number:
HY-139374-50mg
Supplier:
Size:
50 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1931994-81-8

Purity:

98.14

Molecular Formula:

C20H21F3N4O4S

Molecular Weight:

470.47

Mass Spectrometry:

Reference Materials

Alternative Names:

BAY 1834845

Product Description:

Zabedosertib (BAY 1834845) is a selective, orally active IRAK4 inhibitor with immunomodulatory potential, IC50 is 3.55 nM. IRAK4 is a protein kinase involved in signaling innate immune responses from Toll-like receptors[1]. Zabedosertib exhibits anti-inflammatory property against IL-β, LPS (HY-D1056) and Imiquimod (HY-B1080) induced inflammation[2].