PROTAC CDK2/9 Degrader-1
Catalogue number:
HY-130709-25mg
Supplier:
Size:
25 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2408641-24-5
Purity:
99.85
Molecular Formula:
C40H41N13O7
Molecular Weight:
815.84
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PROTAC CDK2/9 Degrader-1 (Compound F3) is a potent dual degrader for CDK2 (DC50=62 nM) and CDK9 (DC50=33 nM). PROTAC CDK2/9 Degrader-1 suppresses prostate cancer PC-3 cell proliferation (IC50=0.12 µM) by effectively blocking the cell cycle in S and G2/M phases. PROTAC CDK2/9 Degrader-1 is a PROTAC by tethering CDK inhibitor with Cereblon ligand[1].