Isatuximab
Catalogue number:
HY-P9976-10mg
Supplier:
Size:
10 mg
Product is available in:
Applications:
Cancer-programmed cell death
Target:
Apoptosis
Alternative Names:
ch38SB19; hu38SB19; SAR-650984
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and ectoenzyme CD38, a protein highly expressed on hematological malignant cells, including those in multiple myeloma (MM). Isatuximab has antitumor activity via multiple biological mechanisms, including antibody-dependent cellular-mediated cytotoxicity, complement-dependent cytotoxicity, antibody-dependent cellular phagocytosis, and direct induction of apoptosis without crosslinking. Isatuximab also directly inhibits CD38 ectoenzyme activity, which is implicated in many cellular functions[1][2].