Enpatoran
Catalogue number:
HY-134581-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2101938-42-3
Purity:
99.80
Molecular Formula:
C16H15F3N4
Molecular Weight:
320.31
Mass Spectrometry:
Reference Materials
Alternative Names:
M5049
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Enpatoran (M5049) is a potent, orally active and dual TLR7/8 inhibitor with IC50s of 11.1 nM and 24.1 nM in HEK293 cells, respectively. Enpatoran is inactive against TLR3, TLR4 and TLR9. Enpatoran can block molecule synthetic ligands and natural endogenous RNA ligands. Enpatoran exhibits excellent pharmacokinetic properties in vivo. Enpatoran can be used for both innate and adaptive autoimmunity blocking research [1].