GSK778
Catalogue number:
HY-136570-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2451862-42-1
Purity:
98.93
Molecular Formula:
C30H33N5O3
Molecular Weight:
511.61
Mass Spectrometry:
Reference Materials
Alternative Names:
iBET-BD1
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GSK778 (iBET-BD1), a chemical probe, is a potent and selective BD1 bromodomain inhibitor of the BET proteins, with IC50s of 75 nM (BRD2 BD1), 41 nM (BRD3 BD1), 41 nM (BRD4 BD1), and 143 nM (BRDT BD1), respectively. GSK778 phenocopies the effects of pan-BET inhibitors in cancer models[1].