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Tolebrutinib

Catalogue number:
HY-109192-5mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£99.00 Special price until 31 Dec 2025
Normal price £109.00
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1971920-73-6

Purity:

98.96

Molecular Formula:

C26H25N5O3

Molecular Weight:

455.51

Alternative Names:

SAR442168; PRN2246

Product Description:

Tolebrutinib (SAR442168) is a potent, selective, orally active and brain-penetrant inhibitor of Bruton tyrosine kinase (BTK), with IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively. Tolebrutinib exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS)[1][2].