MSC-4381
Catalogue number:
HY-132301-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2445185-57-7
Purity:
98.89
Molecular Formula:
C26H20ClN3O6S
Molecular Weight:
537.97
Mass Spectrometry:
Reference Materials
Alternative Names:
MCT4-IN-1
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
MSC-4381 (MCT4-IN-1), a chemical probe, is an orally active and selective monocarboxylate transporter 4 (MCT4/SLC16A3) inhibitor with an IC50 of 77 nM and a Ki of 11 nM. MSC-4381 targets to the cytosolic domain of MCT4. MSC-4381 results in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells. MSC-4381 has the potential for MCT4 transporter inhibition research[1]. MSC-4381 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.