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ART558

Catalogue number:
HY-141520-5mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2603528-97-6

Purity:

99.97

Molecular Formula:

C21H21F3N4O2

Molecular Weight:

418.41

Mass Spectrometry:

Reference Materials

Product Description:

ART558 is a potent, selective and allosteric DNA polymerase theta (Polθ) inhibitor (IC50=7.9 nM). ART558 elicits BRCA-gene synthetic lethality and DNA damage. ART558 can be used for the research of cancer, such as breast cancer[1].