TAK-683 (acetate)
Catalogue number:
HY-P2161B-1mg
Supplier:
Size:
1 mg
Product is available in:
Purity:
99.91
Molecular Weight:
1358.50
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- MSDS: View or download
- Protocol: View or download
Product Description:
TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively[1]. TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer[1][2][4].