www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

MS402

Catalogue number:
HY-120000-5mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£60.00 Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1672684-68-2

Purity:

98.36

Molecular Formula:

C20H19ClN2O3

Molecular Weight:

370.83

Mass Spectrometry:

Reference Materials

Product Description:

MS402 is a BD1-selective BET BrD inhibitor with Kis of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1), BRD4(BD2), BRD3(BD1), BRD3(BD2), BRD2(BD1) and BRD2(BD2), respectively. MS402 blocks Th17 cell differentiation and ameliorates colitis in mice[1].