Fedratinib (hydrochloride hydrate)
Catalogue number:
HY-10409A-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1374744-69-0
Purity:
99.92
Molecular Formula:
C27H40Cl2N6O4S
Molecular Weight:
615.62
Mass Spectrometry:
Reference Materials
Alternative Names:
TG-101348 (hydrochloride hydrate); SAR 302503 (hydrochloride hydrate)
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- MSDS: View or download
- Protocol: View or download
Product Description:
Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research[1][2].