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Lapaquistat acetate

Catalogue number:
HY-16274-5mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

189060-13-7

Purity:

99.10

Molecular Formula:

C33H41ClN2O9

Molecular Weight:

645.14

Mass Spectrometry:

Reference Materials

Alternative Names:

TAK-475

Product Description:

Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway[1]. Lapaquistat acetate is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage. Lapaquistat acetate is used for hypercholesterolemia and mevalonate kinase deficiency (MKD) research[2].