N-Desmethyltamoxifen (hydrochloride)
Catalogue number:
HY-129099A-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
15917-65-4
Purity:
99.93
Molecular Formula:
C25H28ClNO
Molecular Weight:
393.95
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation[1][2][3].