DM4-SMe
Catalogue number:
HY-130082-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
796073-68-2
Purity:
99.99
Molecular Formula:
C39H56ClN3O10S2
Molecular Weight:
826.46
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
DM4-SMe is a metabolite of antibody-maytansin conjugates (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM4-SMe inhibits KB cells with an IC50 of 0.026 nM[1][2].