Azvudine (hydrochloride)
Catalogue number:
HY-19314A-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
Molecular Formula:
C9H12ClFN6O4
Molecular Weight:
322.68
Alternative Names:
RO-0622 (hydrochloride); FNC (hydrochloride)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Azvudine (RO-0622) hydrochloride is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine hydrochloride exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM). Azvudine hydrochloride inhibits NRTI-resistant viral strains[1]. Azvudine (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.