Mitoguazone
Catalogue number:
HY-106634-10mg
Supplier:
Size:
10 mg
Product is available in:
£252.00
Special price until 31 Dec 2025
Normal price £280.00
Shipping is calculated in checkout
Normal price £280.00
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
459-86-9
Purity:
99.33
Molecular Formula:
C5H12N8
Molecular Weight:
184.2
Alternative Names:
Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment[1][2][3][4].