Almonertinib
Catalogue number:
HY-112823-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1899921-05-1
Purity:
99.83
Molecular Formula:
C30H35N7O2
Molecular Weight:
525.64
Mass Spectrometry:
Reference Materials
Alternative Names:
HS-10296
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Almonertinib (HS-10296) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib is used for the research of the non-small cell lung cancer[1][2].