Auto-normalising NGS library preparation kits: plexWell

The plexWell DNA next-generation sequencing (NGS) library preparation kits from seqWell offer a simple and scalable multiplexed workflow for hundreds to thousands of samples in under 3-hours. plexWell’s integrated normalisation technology enables the preparation of balanced library pools without the need for additional sample or library normalisation. Reducing the variability in library concentration and size, these true multiplexing kit saves time and enhances overall sequencing performance with improved multiplexing uniformity.   

Find out about the plexWell normalised library prep technology

Benefits of using these DNA NGS library prep kits
• Self-normalising
• Reduced time and cost for library QC
• Multiplex hundreds to thousands of samples in a single sequencing run
• Uniform insert size and sample read counts
• Compatible with high throughput applications
• Ideal for large-scale sequencing
• plexWell and purePlex libraries compatible with all Illumina™ sequencing platforms

plexWell's simple and scalable workflow

Left: Conventional 8+ hour library prep workflow. Right: plexWell 3-hour workflow. plexWell workflow saves hours over conventional library prep by eliminating the need for time-intensive DNA normalisation and library quantitation. 

Superior tolerance with variable input range

plexWell technology yields balanced multiplexed libraries containing highly uniform insert size distributions and sample read counts.

Applications
• Low-pass whole genome
• scRNA-seq
• Whole human genome
• Amplicons/plasmids, synthetic constructs
• Whole microbial genome
• Metagenomics/microbe screening

Material available for download
Application note: plexWell and metagenomics
Application note: plasmid sequencing
plexWell product brochure

To discuss your requirements or to find out more about the plexWell range, please contact our seqWell specialist.

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