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High-performance antibodies for sensitive, reliable diganostic assay development
Antibodies for diagnostics from Jackson ImmunoResearch are designed to support high-sensitivity immunoassays, rapid diagnostic platforms, and multiplex detection workflows with exceptional specificity and reproducibility. Manufactured using affinity purification and advanced cross-adsorption technologies, these antibodies help minimise non-specific binding and background interference in complex biological samples.
Optimized for ELISA, lateral flow assays (LFAs), fluorescent immunoassays, serological testing, western blotting, and flow cytometry, Jackson ImmunoResearch diagnostic antibodies provide assay developers and researchers with highly reliable reagents for clinical and research applications. With a broad selection of anti-human secondary antibodies, colloidal gold conjugates, and highly cross-adsorbed formats, these reagents support accurate biomarker detection and robust assay performance across a wide range of diagnostic platforms.
Key features
- Highly cross-adsorbed antibodies: minimises species cross-reactivity and background staining
- High-specificity: anti-human secondary antibodies for diagnostic immunoassays
- Colloidal gold conjugates: available for rapid test and point-of-care assay development
- ISO 9001:2015 manufactured products: supporting consistent lot-to-lot reproducibility
What are antibodies for diagnositics?
Diagnostic antibodies are highly specific immunoreagents used to detect target antigens or antibodies within biological samples. Secondary antibodies play a critical role in immunodiagnostic assays by amplifying signal detection and enabling sensitive visualisation using enzymatic, fluorescent, or particulate conjugates.
Jackson ImmunoResearch anti-human secondary antibodies are affinity-purified and extensively validated to ensure reliable detection of human immunoglobulins in clinical and research workflows.
Available specificities include:
| Whole immunoglobulin antibodies | Fragment-specific formats |
|---|---|
| Anti-Human IgG | Fcγ fragment-specific antibodies |
| Anti-Human IgM | F(ab')2 fragment antibodies |
| Anti-Human IgA | Fab fragment antibodies |
| Anti-Human IgE | Light chain specific |
| Anti-Human IgG + IgM detection | Subclass-specific antibodies |
| Combined IgG + IgM + IgA detection | Combined Ig detection |
These formats help improve assay specificity, reduce Fc-mediated binding, and support multiplex assay development.
Highly cross-adsorbed antibodies for diagnostic accuracy
Cross-reactivity can compromise diagnostic assay sensitivity and generate false-positive results. Highly cross-adsorbed secondary antibodies are specifically designed to minimise unwanted interactions with serum proteins and immunoglobulins from non-target species.
Jackson ImmunoResearch highly cross-adsorbed antibodies undergo additional adsorption steps against serum proteins from related species, helping reduce non-specific staining and improve signal clarity in multiplex and multi-species workflows. Highly cross-adsorbed secondary antibodies are particularly valuable for multiplex imaging and assays involving multiple antibody species.
Find out more about benefits of highly cross-adsorbed antibodies.
Colloidal gold conjugates for lateral flow assays
Jackson ImmunoResearch colloidal gold conjugates are widely used in rapid diagnostic tests and lateral flow immunoassays where sensitive visual detection is required. Colloidal gold particles provide excellent visibility, stability, and ease of integration into point-of-care diagnostic platforms. Jackson ImmunoResearch offers 40nm colloidal gold conjugates optimised for reliable membrane flow characteristics and strong visual signal generation.
Typical applications include rapid antigen testing, serological assays, lateral flow immunoassays, point-of-care diagnostics and infectious disease testing.
Choosing the right diagnostic antibody
Selecting the appropriate antibody depends on assay format, sample type, target analyte, and detection method.
| Requirement | Recommended Solution |
|---|---|
| Lateral flow assay development | Colloidal gold conjugates |
| Multiplex fluorescence assays | Highly cross-adsorbed secondary antibodies |
| Low background immunoassays | Cross-adsorbed antibodies |
| Reduced Fc receptor interactions | Fragment-specific antibodies |
| High-sensitivity ELISA | HRP-conjugated secondary antibodies |
| Fluorescent detection workflows | Alexa Fluor® conjugated antibodies |
Available formats
Jackson ImmunoResearch diagnostic antibodies are available in multiple formats to support a wide range of immunoassay platforms.
| Conjugate Options | Host Species Options | Specificity Options |
|---|---|---|
| Alexa Fluor® dyes | Donkey | Anti-IgG (H+L) |
| Cyanine™ dyes | Goat | Fc fragment specific |
| HRP conjugates | Rabbit | F(ab')2 fragment specific |
| Alkaline phosphatase (AP) | Alpaca | |
| Biotin conjugates | Mouse | |
| Colloidal gold conjugates |
Secondary antibodies can be provided in bulk to enable easy scalability of diagnostic manufacturing.
Material available for download
Assay set-up: sandwich ELISA for allergy
Lateral flow immunoassay: methodology, applications, and considerations for use
Jackson ImmunoResearch LM and EM grade colloidal gold
An introduction to surface plasmon resonance
Products
Note: product availability depends on country - see product detail page.
| Details | Cat number & supplier | Size | Price |
| IgG Fraction Monoclonal Mouse Anti-Human IgE (ME.114) 209-002-241 · Jackson ImmunoResearch | 209-002-241 Jackson ImmunoResearch |
0.1 mg |
£272.00
0.1 mg
view
|
| AffiniPure® Rabbit Anti-Human Lactoferrin 309-005-015 · Jackson ImmunoResearch | 309-005-015 Jackson ImmunoResearch |
2 mg |
£166.00
2 mg
view
|
| AffiniPure® Goat Anti-Human IgG + IgM (H+L) 109-005-044 · Jackson ImmunoResearch | 109-005-044 Jackson ImmunoResearch |
2 mg |
£150.00
2 mg
view
|
| AffiniPure® Goat Anti-Human IgA + IgG + IgM (H+L) 109-005-064 · Jackson ImmunoResearch | 109-005-064 Jackson ImmunoResearch |
2 mg |
£150.00
2 mg
view
|
| Rabbit Anti-Human IgG (H+L) 309-001-003 · Jackson ImmunoResearch | 309-001-003 Jackson ImmunoResearch |
2 ml |
£66.00
2 ml
view
|
| AffiniPure® Rabbit Anti-Human IgG (H+L) 309-005-003 · Jackson ImmunoResearch | 309-005-003 Jackson ImmunoResearch |
2 mg |
£150.00
2 mg
view
|
| AffiniPure® Rabbit Anti-Human Serum IgA, α Chain Specific 309-005-011 · Jackson ImmunoResearch | 309-005-011 Jackson ImmunoResearch |
2 mg |
£173.00
2 mg
view
|
| AffiniPure® Rabbit Anti-Human IgA+IgG+IgM (H+L) 309-005-064 · Jackson ImmunoResearch | 309-005-064 Jackson ImmunoResearch |
2 mg |
£182.00
2 mg
view
|
| IgG Fraction Monoclonal Mouse Anti-Human IgE (10A10) 209-002-244 · Jackson ImmunoResearch | 209-002-244 Jackson ImmunoResearch |
0.1 mg |
£285.00
0.1 mg
view
|
