- In this section:
- Download the ChIP-Exo-Seq application note
Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.
Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis
How ChIP-Exo-Seq makes a difference
Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays
Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.
Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation
Materials to download
ChIP-Exo-Seq application note
Products
Note: product availability depends on country - see product detail page.
Details | Cat number & supplier | Size | Price |
Anti-ZNF232 HPA028611-25ul · Atlas Antibodies | HPA028611-25ul Atlas Antibodies |
25 µl |
£342.00
25 µl
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Anti-PRRX2 HPA026808-25ul · Atlas Antibodies | HPA026808-25ul Atlas Antibodies |
25 µl |
£228.00
25 µl
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Anti-GTF2I HPA026638-25ul · Atlas Antibodies | HPA026638-25ul Atlas Antibodies |
25 µl |
£306.00
25 µl
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Anti-TCF4 HPA025958-25ul · Atlas Antibodies | HPA025958-25ul Atlas Antibodies |
25 µl |
£306.00
25 µl
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Anti-ZNF770 HPA024518-25ul · Atlas Antibodies | HPA024518-25ul Atlas Antibodies |
25 µl |
£228.00
25 µl
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Anti-GATAD2A HPA024373-25ul · Atlas Antibodies | HPA024373-25ul Atlas Antibodies |
25 µl |
£342.00
25 µl
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Anti-SUPT3H HPA024371-25ul · Atlas Antibodies | HPA024371-25ul Atlas Antibodies |
25 µl |
£228.00
25 µl
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Anti-NFATC2 HPA024369-25ul · Atlas Antibodies | HPA024369-25ul Atlas Antibodies |
25 µl |
£306.00
25 µl
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Anti-ZSCAN2 HPA024331-25ul · Atlas Antibodies | HPA024331-25ul Atlas Antibodies |
25 µl |
£342.00
25 µl
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Anti-NCOA3 HPA024210-25ul · Atlas Antibodies | HPA024210-25ul Atlas Antibodies |
25 µl |
£306.00
25 µl
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Anti-NFKB1 HPA027305-25ul · Atlas Antibodies | HPA027305-25ul Atlas Antibodies |
25 µl |
£245.00
25 µl
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Anti-ZNF277 HPA027307-25ul · Atlas Antibodies | HPA027307-25ul Atlas Antibodies |
25 µl |
£228.00
25 µl
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Anti-MED8 HPA028438-25ul · Atlas Antibodies | HPA028438-25ul Atlas Antibodies |
25 µl |
£228.00
25 µl
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Anti-DMAP1 HPA028419-25ul · Atlas Antibodies | HPA028419-25ul Atlas Antibodies |
25 µl |
£342.00
25 µl
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Anti-MYOG HPA028336-25ul · Atlas Antibodies | HPA028336-25ul Atlas Antibodies |
25 µl |
£306.00
25 µl
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