Chip-exo-Seq antibodies

Atlas Antibodies offers a selection of ChIP-exo-Seq validated antibodies, which are high-specificity antibodies designed for use in ChIP-exo, a powerful method for mapping protein-DNA interactions at base-pair resolution. Validated using exonuclease-treated chromatin immunoprecipitation followed by sequencing, these antibodies ensure precise and sharp detection of binding sites, minimising background and off-target signals. They are ideal for researchers studying transcription factors, histone modifications, and regulatory elements where accuracy is critical. Backed by data from the Human Protein Atlas and independent validation labs, these antibodies provide confidence in results and are optimised for high-resolution epigenomic research.

Benefits of using Atlas Chip-exo-Seq antibodies
• Achieve precise protein-DNA binding site mapping
• Minimise background noise
• Ensure reliable mapping of transcription factors & chromatin-associated proteins
• Observe a 50% validation success rate, more than double the industry average
• Enables comprehensive epigenetic analysis

How ChIP-Exo-Seq makes a difference

Why ChIP-Exo-Seq makes a difference

Atlas ChIP-exo-Seq antibodies demonstrate exceptional specificity and reproducibility in ChIP-Exo-Seq assays

Establishing a Higher Benchmark for Antibodies Performance

Figure: ChIP-exo-Seq composite graph for Anti-ELF1 (HPA001755, Lot R00715) tested in K562 cells. Strand-specific reads are shown in blue (forward) and red (reverse), with IgG controls in black (forward) and grey (reverse), plotted relative to a composite set of reference binding sites. The data is smoothed using a 21 bp moving average across 460 sites. The antibody demonstrates strong target-specific enrichment compared to the non-specific IgG control and clearly defines the structural organization at the binding site. Data was generated by Prof. B. F. Pugh’s laboratory at Cornell University, Ithaca, NY, USA.

Applications
High-resolution protein-DNA interaction mapping
Epigenetic regulation studies
Transcriptional regulation analysis
Enhancer and promoter characterisation
Super-resolution chromatin architecture mapping
Comparative genomics & evolutionary studies
Disease mechanism investigation
Drug target discovery & validation

Materials to download
ChIP-Exo-Seq application note

Products

Note: product availability depends on country - see product detail page.

Details	Cat number & supplier	Size	Price
Anti-GABPA HPA003258-25ul · Atlas Antibodies	HPA003258-25ul Atlas Antibodies	25 µl	£228.00 25 µl view
Anti-MEIS2 HPA003256-25ul · Atlas Antibodies	HPA003256-25ul Atlas Antibodies	25 µl	£306.00 25 µl view
Anti-OLIG2 HPA003254-25ul · Atlas Antibodies	HPA003254-25ul Atlas Antibodies	25 µl	£306.00 25 µl view
Anti-ZNF777 HPA003252-25ul · Atlas Antibodies	HPA003252-25ul Atlas Antibodies	25 µl	£228.00 25 µl view
Anti-MED12 HPA003185-25ul · Atlas Antibodies	HPA003185-25ul Atlas Antibodies	25 µl	£306.00 25 µl view
Anti-ZNF148 HPA001656-25ul · Atlas Antibodies	HPA001656-25ul Atlas Antibodies	25 µl	£342.00 25 µl view
Anti-ELK3 HPA001600-25ul · Atlas Antibodies	HPA001600-25ul Atlas Antibodies	25 µl	£228.00 25 µl view
Anti-ZBTB22 HPA043848 · Atlas Antibodies	HPA043848 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-POLR1C HPA031010 · Atlas Antibodies	HPA031010 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-E2F6 HPA075185 · Atlas Antibodies	HPA075185 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-TAL1 HPA073983 · Atlas Antibodies	HPA073983 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-NR0B1 HPA067207 · Atlas Antibodies	HPA067207 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZNF184 HPA064793 · Atlas Antibodies	HPA064793 Atlas Antibodies	100 µl	£455.00 100 µl view
Anti-PRRX1 HPA063566 · Atlas Antibodies	HPA063566 Atlas Antibodies	100 µl	£429.00 100 µl view
Anti-ZKSCAN3 HPA060116 · Atlas Antibodies	HPA060116 Atlas Antibodies	100 µl	£455.00 100 µl view

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Download the ChIP-Exo-Seq application note