InVivoMAb™ and InVivoPlus™ antibodies from Bio X Cell are trusted, high-performance monoclonal antibodies for in vivo research. Also suitable for in vitro use, these ultra-pure, low endotoxin antibodies are free from preservatives, stabilisers and carrier proteins - making them ideal for use in preclinical studies such as immunotherapy research, tumour models and autoimmune disease investigations.
The InVivoMAb product line includes a wide selection of research-grade in vivo antibodies, such as the well-cited anti-PD-1 clone RMP1-14 and anti-PD-L1 clone 10F.9G2, commonly used to investigate immune checkpoint inhibition and boost T cell responses in cancer models. These carrier-free antibodies for tumour models are specifically formulated for use in mouse models and other in vivo systems requiring high purity and reproducibility.
For studies with heightened quality demands, InVivoPlus antibodies undergo additional testing, including endotoxin screening, aggregation analysis and murine pathogen detection. With proven batch-to-batch consistency and rigorous QC, InVivoPlus are the ideal choice for sensitive in vivo experiments.
Benefits of using InVivoMAb and InVivoPlus
- Monoclonal antibodies for in vivo research
- >95% purity
- Ultra-low endotoxin antibodies
- Free of preservatives, stabilisers & carrier proteins
- Block, neutralise, activate or deplete targets
- PD-1 & CTLA-4 in vivo antibodies available
- Ideal for preclinical studies, including immunotherapy research, tumour medals & autoimmune disease investigation
- Cited in over 20,000 publications
Differences between InVivoMAb and InVivoPlus
Tested for: | InVivoMAb | InVivoPlus |
---|---|---|
Binding validation By ELISA, flow cytometry or immunoblot |
No | Yes |
Screening for murine pathogens By ultra-sensitive real-time PCR |
No | Yes |
Screening for antibody aggregation By size exclusion chromatography |
No | Yes |
Endotoxin By LAL gel clotting assay |
<2EU/mg | <1EU/mg |
Purity By SDS-PAGE |
>95% | >95% |
Preservative/stabiliser/carrier protein-free | Yes | Yes |
Formulated for in vivo use | Yes | Yes |
Catalogue number format | Begins with BE | Begins with BP |
Applications
Cancer immunotherapy
Tumour immunology
Immune checkpoint blocking
Mouse cell specific depletion
Cytokine neutralisation
Agonistic/cell activation
Receptor blocking
In vivo CD4+ T cell depletion
Downloadable materials
Bio X Cell cancer brochure
Bio X Cell depletion antibodies brochure
Bio X Cell immunology brochure
Products
Note: product availability depends on country - see product detail page.
Details | Cat number & supplier | Size | Price |
InVivoMAb anti-mouse TNFα BE0058-R001mg · Bio X Cell | BE0058-R001mg Bio X Cell |
1 mg |
£145.00
1 mg
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InVivoMAb anti-mouse MHC Class II (I-A/I-E) BE0108-R005mg · Bio X Cell | BE0108-R005mg Bio X Cell |
5 mg |
£530.00
5 mg
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InVivoPlus anti-mouse CD71 (TfR1) BP0175-R025mg · Bio X Cell | BP0175-R025mg Bio X Cell |
25 mg |
£2310.00
25 mg
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InVivoMAb mouse IgG2a isotype control, unknown specificity BE0085-R001mg · Bio X Cell | BE0085-R001mg Bio X Cell |
1 mg |
£145.00
1 mg
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InVivoMAb recombinant CTLA-4-Ig (hum/hum) BE0099-R005mg · Bio X Cell | BE0099-R005mg Bio X Cell |
5 mg |
£530.00
5 mg
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InVivoMAb anti-mouse LPAM-1 (Integrin α4β7) BE0034-R001mg · Bio X Cell | BE0034-R001mg Bio X Cell |
1 mg |
£145.00
1 mg
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InVivoMAb anti-mouse GITR BE0063-R001mg · Bio X Cell | BE0063-R001mg Bio X Cell |
1 mg |
£145.00
1 mg
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InVivoMAb anti-mouse 2C TCR BE0069-R001mg · Bio X Cell | BE0069-R001mg Bio X Cell |
1 mg |
£145.00
1 mg
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InVivoMAb polyclonal rat IgG BE0094-R005mg · Bio X Cell | BE0094-R005mg Bio X Cell |
5 mg |
£530.00
5 mg
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InVivoMAb anti-mouse CD80 (B7-1) BE0024-R001mg · Bio X Cell | BE0024-R001mg Bio X Cell |
1 mg |
£145.00
1 mg
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InVivoMAb anti-mouse IFNγR (CD119) BE0029-R001mg · Bio X Cell | BE0029-R001mg Bio X Cell |
1 mg |
£145.00
1 mg
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InVivoMAb anti-mouse CD28 BE0015-5-R001mg · Bio X Cell | BE0015-5-R001mg Bio X Cell |
1 mg |
£145.00
1 mg
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InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin BE0090-R001mg · Bio X Cell | BE0090-R001mg Bio X Cell |
1 mg |
£145.00
1 mg
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InVivoPlus anti-mouse IL-4 BP0045-R005mg · Bio X Cell | BP0045-R005mg Bio X Cell |
5 mg |
£690.00
5 mg
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InVivoMAb anti-mouse CD54 (ICAM-1) BE0020-1-R001mg · Bio X Cell | BE0020-1-R001mg Bio X Cell |
1 mg |
£145.00
1 mg
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