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In vivo antibodies: InVivoMAb and InVivoPlus

InVivoMAb™ and InVivoPlus™ antibodies from Bio X Cell are trusted, high-performance monoclonal antibodies for in vivo research. Also suitable for in vitro use, these ultra-pure, low endotoxin antibodies are free from preservatives, stabilisers and carrier proteins - making them ideal for use in preclinical studies such as immunotherapy research, tumour models and autoimmune disease investigations.

The InVivoMAb product line includes a wide selection of research-grade in vivo antibodies, such as the well-cited anti-PD-1 clone RMP1-14 and anti-PD-L1 clone 10F.9G2, commonly used to investigate immune checkpoint inhibition and boost T cell responses in cancer models. These carrier-free antibodies for tumour models are specifically formulated for use in mouse models and other in vivo systems requiring high purity and reproducibility.

For studies with heightened quality demands, InVivoPlus antibodies undergo additional testing, including endotoxin screening, aggregation analysis and murine pathogen detection. With proven batch-to-batch consistency and rigorous QC, InVivoPlus are the ideal choice for sensitive in vivo experiments.

Benefits of using InVivoMAb and InVivoPlus

  • Monoclonal antibodies for in vivo research
  • >95% purity
  • Ultra-low endotoxin antibodies
  • Free of preservatives, stabilisers & carrier proteins
  • Block, neutralise, activate or deplete targets
  • PD-1 & CTLA-4 in vivo antibodies available
  • Ideal for preclinical studies, including immunotherapy research, tumour medals & autoimmune disease investigation
  • Cited in over 20,000 publications


Differences between InVivoMAb and InVivoPlus

Tested for: InVivoMAb InVivoPlus
Binding validation
By ELISA, flow cytometry or immunoblot
No Yes
Screening for murine pathogens
By ultra-sensitive real-time PCR
No Yes
Screening for antibody aggregation
By size exclusion chromatography
No Yes
Endotoxin
By LAL gel clotting assay
<2EU/mg <1EU/mg
Purity
By SDS-PAGE
>95% >95%
Preservative/stabiliser/carrier protein-free Yes Yes
Formulated for in vivo use Yes Yes
Catalogue number format Begins with BE Begins with BP


Applications
Cancer immunotherapy
Tumour immunology
Immune checkpoint blocking 
Mouse cell specific depletion
Cytokine neutralisation 
Agonistic/cell activation 
Receptor blocking
In vivo CD4+ T cell depletion

Downloadable materials
Bio X Cell cancer brochure
Bio X Cell depletion antibodies brochure
Bio X Cell immunology brochure

in vivo mab,in vivo plus,in vivo antibody,in vivo ab

Products

Note: product availability depends on country - see product detail page.

Details Cat number & supplier Size Price
InVivoPlus anti-mouse CD25 (IL-2Rα) BP0012-R005mg · Bio X Cell
BP0012-R005mg
Bio X Cell
5 mg £690.00
5 mg
view
InVivoMAb anti-mouse CD28 BE0015-1-R025mg · Bio X Cell
BE0015-1-R025mg
Bio X Cell
25 mg £1774.00
25 mg
view
InVivoPlus anti-mouse LAG-3 BP0174-R050mg · Bio X Cell
BP0174-R050mg
Bio X Cell
50 mg £3477.00
50 mg
view
InVivoMAb anti-mouse CD45RB BE0019-R025mg · Bio X Cell
BE0019-R025mg
Bio X Cell
25 mg £1774.00
25 mg
view
InVivoMAb anti-mouse/human CD44 BE0039-R025mg · Bio X Cell
BE0039-R025mg
Bio X Cell
25 mg £1774.00
25 mg
view
InVivoPlus anti-mouse CD25 (IL-2Rα) BP0012-R025mg · Bio X Cell
BP0012-R025mg
Bio X Cell
25 mg £2310.00
25 mg
view
InVivoPlus anti-mouse NK1.1 BP0036-R050mg · Bio X Cell
BP0036-R050mg
Bio X Cell
50 mg £3477.00
50 mg
view
InVivoPlus anti-human MHC Class I (HLA-A, HLA-B, HLA-C) BP0079-R005mg · Bio X Cell
BP0079-R005mg
Bio X Cell
5 mg £690.00
5 mg
view
InVivoMAb anti-mouse CD28 BE0015-1-R050mg · Bio X Cell
BE0015-1-R050mg
Bio X Cell
50 mg £2671.00
50 mg
view
InVivoMAb polyclonal mouse IgG BE0093-R100mg · Bio X Cell
BE0093-R100mg
Bio X Cell
100 mg £3780.00
100 mg
view
InVivoPlus anti-mouse CD8α BP0117-R050mg · Bio X Cell
BP0117-R050mg
Bio X Cell
50 mg £3477.00
50 mg
view
InVivoMAb anti-mouse IL-10R (CD210) BE0050-R050mg · Bio X Cell
BE0050-R050mg
Bio X Cell
50 mg £2671.00
50 mg
view
InVivoMAb rat IgG2a isotype control, anti-trinitrophenol BE0089-R050mg · Bio X Cell
BE0089-R050mg
Bio X Cell
50 mg £2671.00
50 mg
view
InVivoMAb anti-mouse/human CD11b BE0007-R050mg · Bio X Cell
BE0007-R050mg
Bio X Cell
50 mg £2671.00
50 mg
view
InVivoPlus anti-mouse TNFα BP0058-R100mg · Bio X Cell
BP0058-R100mg
Bio X Cell
100 mg £4917.00
100 mg
view