DNA & RNA purification doesn't have to be difficult, which is where Zymo come in. Their range of kits are designed to make your workflows refreshingly simple.
ZymoPURE
"I’ve just had a chance to try this kit out and I really like it! Even without a vacuum manifold it was SO much simpler/faster than the old school Qiagen kits that the lab I have just joined currently use, and saves me repeated journeys to and from the ultracentrifuge in the basement ‘ZymoPURE II Plasmid Maxiprep."
"We have now tested both midi and mini preps and had a pretty good experience with mini preps. What I mostly appreciated is the visual aspect (colour-coded bottles and the possibility to visually determine if the reaction has worked - it was generally very easy to follow). The yield was also acceptable (2-10 ug per sample). The only issue that seems to be unavoidable is that columns don't have lids which makes it impossible to elute fully sterile DNA (we would do it under a hood to preserve sterility which is needed to further use samples on cell cultures."
"I just finished using the Zymo Maxi prep kit and I'm really really impressed. I got a great yield, 260/280 ratio was perfect and it was so easy and fast, it felt more like doing a miniprep. I can't really express how happy I am with it I feel that our group is sure to switch to Zymo Maxi prep kits in the future after we finish off a backlog of old columns we had. Thank you. I'm so happy, I can't explain how much work I had to do today and how much this has simplified everything."
"I'm happy to report that the kit was a success even with our more difficult plasmid. The yields have increased. I will be looking to put in an order for the kit."
"Briefly, the Zymo plasmid purification kit, I like it, because it is easy and already includes all the steps that make everything straightforward for me, and I'll order a kit to start using here."
"I really like the kit and managed to get a good yield from my DNA prep. It was a mutagenesis prep so I wasn’t entirely sure whether it would work well, but I was pleasantly surprised. The colour coding is an excellent idea, it did make the process much easier, and the idea of using the filters – really clever. And so much quicker!"
"We actually use the Thermo midiprep kit so in comparison to that, the Zymo kit was definitely faster and easier to use. The quantity of the DNA was higher although I cannot judge about the quality before I do a transfection with it."
"I have tried both kits now. They were both good, worked well and were easy to use once I figured out what each part was!"
"I’ve just had a chance to try this kit out and I really like it! Even without a vacuum manifold it was SO much simpler/faster than the old school Qiagen kits that the lab I have just joined currently use, and saves me repeated journeys to and from the ultracentrifuge in the basement. It would be great to get an introductory discount if possible, so that I can try to convert the old-timers (to quote one of them: “16 minutes?! I’ll believe it when I see it..”)"
"I must say that the Zymo midiprep kit was a lot easier to use and plasmid isolation was a lot quicker to complete compared to the promega kit we have been using in the lab. I have recommended to my PI and he has approved that we use Zymo products henceforth."
"The Zymo maxiprep system is the simplest, fastest and most foolproof system I have ever used. I will never go back to any other kit as long as I am able to use the Zymo kit!"
DirectZol
"We are encouraged by safety rules to move away from phenol-based products. But they are indispensable in some procedure. Without your kit and especially columns, the procedure would be longer and much more phenol and plastic consumables would be used."
"In general, I had no issues with handling, it was fast and easy. In terms of yield it has given me less material as below but still sufficient for our needs."
"We are overall pleased with Direct-zol RNA Microprep kit (after a small protocol adjustment; as you may remember). We obtained very good quality sequencing data for our RNA-seq analysis, and we are planning to use this kit in the future."
"Firstly, the Direct-Zol RNA microprep worked really nicely, it was very quick and easy and yield/quality was as good as we are used to."
"Yes I have tried it out. It worked rather well actually – especially as I tested with some particularly sparse cell samples which other methods would have failed with. The RNA was clean and abundant."
"I have completed a comparison experiment last month and it seems to be quite positive so I ended up purchasing the kit from your company. I am interested in small RNA from small tissue in mouse so it is preferable to go for a column-based kit considering there is a report about enrichment bias when doing ethanol precipitation starting from limited amount of RNA."
"Overall, I was very happy with the kit. The two main advantages were the speed at which samples were processed and the consistency across the samples (with respect to UV spec analysis for RNA purity and concentrations). I have also spoken with a colleague who uses these columns for RNAseq analysis and they recommend them too."
DNA Clean & Concentrator-5
"I’ve tested the sample and are happy with it. I will probably suggest re-ordering when finished if compatible with price of similar products. Easy to use and good instructions. Our results look good as well and don’t seem to be altered in the purification step. So over all very happy with sample and product."
Zymoclean Gel DNA Recovery Kit
"In my view it is probably the best DNA extraction kit I used so far (and I am working in the field for several years)- "
"I tried the D4001S Zymoclean™ Gel DNA Recovery Kit. It works really well. I prepared the DNA constructs (2 constructs) for generating a new cell line. Since I already got the cell line and have no plan for cloning recently, thanks very much for your kind offer now, I email you for a quote once I hope to buy a full kit."
DNA/RNA shield
"I tested the Shield and it seems working fine for my applications. Additionally, I received feedback from colleagues at Zymo whom I met at the FEMS conference in Hamburg."
"Indeed we trialled the DNA/RNA Shield (R1100-8-S) and after being happy with the results, we purchased an additional bottle of the solution."
"I am very pleased with this product and I planned to use it on a regular basis whenever sample preservation is required. It has all the required features (e.g. it preserves RNA too!) and also preformed as absolutely the best when we tested it against similar preservatives from other companies. DNA/RNA shield is absolutely the best! The main project where I am using DNA/RNA shield is Wilder Blean conducted in collaboration with Kent Wildlife Trust and Wildwood Trust. In short it seeks to evaluate the impact of the presence of the European Bison in soil biodiversity. It has already attracted quite an attention from various kinds of media, TV, internet, social media, where we are happy to discuss also revolutionary products allowing for this project to happen. It has also been included as one of the projects within the newest gallery themed Fixing Our Broken Planet at the NHM. I..."
"We used the DNA/RNA shield as part of a bespoke inactivation, lysis, and purification of DNA from challenging bacterial isolates, many of which produce a mucoidal extract using other methods. The DNA/RNA shield managed to help produce a DNA extract that was not viscous and also contained no viable cells."