Abdelnabi, R., Geraets, J.A., Ma, Y., Mirabelli, C., Flatt, J.W., Domanska, A., Delang, L., Jochmans, D., Kumar, T.A., Jayaprakash, V., Sinha, B.N., Leyssen, P., Butcher, S.J. and Neyts, J. (2019). A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses. PLOS Biology, [online] 17(6), p.e3000281. Available at: https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000281 [Accessed 3 Sep. 2019].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: Vero A
Nucleic acid: viral RNA
Application: Virus production
Annamalai, A.S., Pattnaik, A., Sahoo, B.R., Guinn, Z.P., Bullard, B.I., Weaver, E.A., Steffen, D., Natarajan, S.K., Petro, T.M. and Pattnaik, A.K. (2019). An Attenuated Zika Virus Encoding Non-Glycosylated Envelope (E) and Non-Structural Protein 1 (NS1) Confers Complete Protection Against Lethal Challenge in a Mouse Model. [online] Vaccines. Available at: https://pubmed.ncbi.nlm.nih.gov/31547297-an-attenuated-zika-virus-encoding-non-glycosylated-envelope-e-and-non-structural-protein-1-ns1-confers-complete-protection-against-lethal-challenge-in-a-mouse-model/ [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: Vero
Nucleic acid: viral RNA
Application: Virus production
Baidaliuk, A., Miot, E.F., Lequime, S., Moltini-Conclois, I., Delaigue, F., Dabo, S., Dickson, L.B., Aubry, F., Merkling, S.H., Cao-Lormeau, V.M. and Lambrechts, L. (2019). Cell-Fusing Agent Virus Reduces Arbovirus Dissemination in Aedes Aegypti Mosquitoes In Vivo. [online] Journal of virology. Available at: https://pubmed.ncbi.nlm.nih.gov/31243123-cell-fusing-agent-virus-reduces-arbovirus-dissemination-in-aedes-aegypti-mosquitoes-in-vivo/ [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: C6/36
Nucleic acid: Viral RNA
Application: Virus production
Bang, B.-R., Li, M., Tsai, K.-N., Aoyagi, H., Lee, S.-A., Machida, K., Aizaki, H., Jung, J.U., Ou, J.-H.J. and Saito, T. (2019). Regulation of Hepatitis C Virus Infection by Cellular Retinoic Acid Binding Proteins through the Modulation of Lipid Droplet Abundance. Journal of Virology, [online] 93(8). Available at: https://jvi.asm.org/content/93/8/e02302-18 [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HuH7.5
Nucleic acid: RNA
Application: Transient transfection
Beachboard, D.C., Park, M., Vijayan, M., Snider, D.L., Fernando, D.J., Williams, G.D., Stanley, S., McFadden, M.J. and Horner, S.M. (2019). The small GTPase RAB1B promotes antiviral innate immunity by interacting with TNF receptor–associated factor 3 (TRAF3). Journal of Biological Chemistry, [online] 294(39), pp.14231–14240. Available at: https://www.jbc.org/content/294/39/14231 [Accessed 26 Feb. 2020]
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HEK 293T
Nucleic acid: RNA
Application: Transient transfection
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HuH7
Nucleic acid: RNA
Application: Transient Transfection
Devoldere, J., Wels, M., Peynshaert, K., Dewitte, H., De Smedt, S.C. and Remaut, K. (2019). The obstacle course to the inner retina: Hyaluronic acid-coated lipoplexes cross the vitreous but fail to overcome the inner limiting membrane. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, [online] 141, pp.161–171. Available at: https://www.ncbi.nlm.nih.gov/pubmed/31150809 [Accessed 2 Dec. 2019].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: Vitreous cells (bovine, primary)
Nucleic acid: mRNA
Application: Gene/Protein Expression
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: MIO-M1
Nucleic acid: mRNA
Application: Gene/protein expression
Dubankova, A., Horova, V., Klima, M. and Boura, E. (2019). Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation. Journal of Structural Biology, [online] 208(2), pp.92–98. Available at: https://www.sciencedirect.com/science/article/pii/S1047847719301741 [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HeLa
Nucleic acid: Viral RNA
Application: Gene/Pprotein expression
Harichandran, K., Shen, Y., Tsoris, S.S., Lee, S.-C. and Casey, J.L. (2019). Hepatitis Delta Antigen Regulates mRNA and Antigenome RNA Levels during Hepatitis Delta Virus Replication. Journal of Virology, [online] 93(8). Available at: https://jvi.asm.org/content/93/8/e01989-18/figures-only [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HuH7
Nucleic acid: RNA
Application: Gene/protein expression
Lin, D., Inoue, T., Chen, Y.J., Chang, A., Tsai, B. and Tai, A.W. (2019). The ER Membrane Protein Complex Promotes Biogenesis of Dengue and Zika Virus Non-structural Multi-pass Transmembrane Proteins to Support Infection. [online] Cell reports. Available at: https://pubmed.ncbi.nlm.nih.gov/31067454-the-er-membrane-protein-complex-promotes-biogenesis-of-dengue-and-zika-virus-non-structural-multi-pass-transmembrane-proteins-to-support-infection/ [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HuH7.5.1
Nucleic acid: Viral RNA
Application: Virus production
Linsalata, A.E., He, F., Malik, A.M., Glineburg, M.R., Green, K.M., Natla, S., Flores, B.N., Krans, A., Archbold, H.C., Fedak, S.J., Barmada, S.J. and Todd, P.K. (2019). DDX3X and Specific Initiation Factors Modulate FMR1 Repeat-Associated non-AUG-initiated Translation. [online] EMBO reports. Available at: https://pubmed.ncbi.nlm.nih.gov/31347257-ddx3x-and-specific-initiation-factors-modulate-fmr1-repeat-associated-non-aug-initiated-translation/ [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HeLa
Nucleic acid: RNA
Application: Gene/protein expression
Murai, K., Honda, M., Shirasaki, T., Shimakami, T., Omura, H., Misu, H., Kita, Y., Takeshita, Y., Ishii, K., Takamura, T., Urabe, T., Shimizu, R., Okada, H., Yamashita, T., Sakai, Y. and Kaneko, S. (2019). Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity. Cell Host & Microbe, [online] 25(4), pp.588–601.e7. Available at: https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(19)30111-8 [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HuH7.5
Nucleic acid: Viral RNA
Application: Virus production
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: KH
Nucleic acid: Viral RNA
Application: Virus production
Netzler, N.E., Enosi Tuipulotu, D., Vasudevan, S.G., Mackenzie, J.M. and White, P.A. (2019). Antiviral Candidates for Treating Hepatitis E Virus Infection. [online] Antimicrobial agents and chemotherapy. Available at: https://pubmed.ncbi.nlm.nih.gov/30885901-antiviral-candidates-for-treating-hepatitis-e-virus-infection/ [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HuH7
Nucleic acid: viral RNA
Application: Virus production
Nishiyama, T., Kobayashi, T., Jirintai, S., Kii, I., Nagashima, S., Prathiwi Primadharsini, P., Nishizawa, T. and Okamoto, H. (2019a). Screening of Novel Drugs for Inhibiting Hepatitis E Virus Replication. [online] Journal of virological methods. Available at: https://pubmed.ncbi.nlm.nih.gov/31004661-screening-of-novel-drugs-for-inhibiting-hepatitis-e-virus-replication/ [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: PLC/PRF/5
Nucleic acid: viral RNA
Application: Gene/protein expression
Nishiyama, T., Kobayashi, T., Jirintai, S., Nagashima, S., Primadharsini, P.P., Nishizawa, T. and Okamoto, H. (2019b). Antiviral candidates against the hepatitis E virus (HEV) and their combinations inhibit HEV growth in in vitro. Antiviral Research, [online] 170, p.104570. Available at: https://www.sciencedirect.com/science/article/abs/pii/S016635421930316X [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: PLC/PRF/5
Nucleic acid: Viral RNA
Application: Virus production
Pardi, N., LaBranche, C.C., Ferrari, G., Cain, D.W., Tombácz, I., Parks, R.J., Muramatsu, H., Mui, B.L., Tam, Y.K., Karikó, K., Polacino, P., Barbosa, C.J., Madden, T.D., Hope, M.J., Haynes, B.F., Montefiori, D.C., Hu, S.-L. and Weissman, D. (2019). Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques. Molecular Therapy - Nucleic Acids, [online] 15, pp.36–47. Available at: https://www.sciencedirect.com/science/article/pii/S2162253119300617 [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HEK 293T
Nucleic acid: mRNA
Application: Gene/protein expression
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HEK 293-F (Freestyle)
Nucleic acid: mRNA
Application: Gene/protein expression
Pulos-Holmes, M.C., Srole, D.N., Juarez, M.G., Lee, A.S.-Y., McSwiggen, D.T., Ingolia, N.T. and Cate, J.H. (2019). Repression of ferritin light chain translation by human eIF3. eLife, [online] 8, p.e48193. Available at: https://elifesciences.org/articles/48193 [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: Hep G2
Nucleic acid: mRNA
Application: Gene/protein expression
Rivera-Serrano, E.E., González-López, O., Das, A. and Lemon, S.M. (2019). Cellular Entry and Uncoating of Naked and Quasi-Enveloped Human Hepatoviruses. [online] eLife. Available at: https://pubmed.ncbi.nlm.nih.gov/30801249-cellular-entry-and-uncoating-of-naked-and-quasi-enveloped-human-hepatoviruses/ [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HuH7.5
Nucleic acid: viral RNA
Application: Gene/protein expression
Russick, J., Delignat, S., Milanov, P., Christophe, O., Boros, G., Denis, C.V., Lenting, P.J., Kaveri, S.V. and Lacroix-Desmazes, S. (2019). Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII-encoding mRNA. Haematologica, [online] p.haematol.2018.210583. Available at: http://www.haematologica.org/content/haematol/early/2019/07/08/haematol.2018.210583.full.pdf [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HEK 293
Nucleic acid: mRNA
Application: Gene/protein expression
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: Monocyte derived dendritic cells
Nucleic acid: mRNA
Application: Gene/Protein Expression
Umrath, F., Steinle, H., Weber, M., Wendel, H.-P., Reinert, S., Alexander, D. and Avci-Adali, M. (2019). Generation of iPSCs from Jaw Periosteal Cells Using Self-Replicating RNA. International Journal of Molecular Sciences, [online] 20(7), p.1648. Available at: https://www.mdpi.com/1422-0067/20/7/1648 [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: Jaw periosteal cells (JPCs)
Nucleic acid: RNA
Application: Gene/protein expression
Yamane, D., Feng, H., Rivera-Serrano, E.E., Selitsky, S.R., Hirai-Yuki, A., Das, A., McKnight, K.L., Misumi, I., Hensley, L., Lovell, W., González-López, O., Suzuki, R., Matsuda, M., Nakanishi, H., Ohto-Nakanishi, T., Hishiki, T., Wauthier, E., Oikawa, T., Morita, K., Reid, L.M., Sethupathy, P., Kohara, M., Whitmire, J.K. and Lemon, S.M. (2019). Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses. Nature Microbiology, [online] 4(7), pp.1096–1104. Available at: https://www.nature.com/articles/s41564-019-0425-6 [Accessed 26 Feb. 2020].
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: HuH7.5
Nucleic acid: viral RNA
Application: Virus production
Product usage
Product: TransIT®-mRNA Transfection Kit
Cell type: PH5CH8
Nucleic acid: viral RNA
Application: Virus production