Baker-Williams, A.J., Hashmi, F., Budzyński, M.A., Woodford, M.R., Gleicher, S., Himanen, S.V., Makedon, A.M., Friedman, D., Cortes, S., Namek, S., Stetler-Stevenson, W.G., Bratslavsky, G., Bah, A., Mollapour, M., Sistonen, L. and Bourboulia, D. (2019). Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis. Cell Reports, [online] 28(7), pp.1894-1906.e6. Available at: https://www.cell.com/cell-reports/pdf/S2211-1247(19)30949-0.pdf [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: HEK 293T
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Crona, D.J., Skol, A.D., Leppänen, V.-M., Glubb, D.M., Etheridge, A.S., Hilliard, E., Peña, C.E., Peterson, Y.K., Klauber-DeMore, N., Alitalo, K.K. and Innocenti, F. (2018). Genetic variants of VEGFA and FLT4 are determinants of survival in renal cell carcinoma patients treated with sorafenib. Cancer Research. [online] Available at: https://cancerres.aacrjournals.org/content/early/2018/11/01/0008-5472.CAN-18-1089 [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: TIME
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: LPEC
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: TIME
Nucleic acid: Plasmid DNA
Application: Stable transfection
Davuluri, G., Giusto, M., Chandel, R., Welch, N., Alsabbagh, K., Kant, S., Kumar, A., Kim, A., Gangadhariah, M., Ghosh, P.K., Tran, U., Krajcik, D.M., Vasu, K., DiDonato, A.J., DiDonato, J.A., Willard, B., Monga, S.P., Wang, Y., Fox, P.L., Stark, G.R., Wessely, O., Esser, K.A. and Dasarathy, S. (2019). Impaired Ribosomal Biogenesis by Noncanonical Degradation of β-Catenin during Hyperammonemia. Molecular and Cellular Biology, [online] 39(16). Available at: https://mcb.asm.org/content/39/16/e00451-18 [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: C2C12
Nucleic acid: shRNA-encoding plasmid DNA
Application: Gene knockdown
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: C2C12
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Du, H., Wang, P., Li, L., Amato, N.J. and Wang, Y. (2019). Cytotoxic and Mutagenic Properties of C1’ and C3’-Epimeric Lesions of 2’-Deoxyribonucleosides in Human Cells. [online] ACS chemical biology. Available at: https://pubmed.ncbi.nlm.nih.gov/30768892-cytotoxic-and-mutagenic-properties-of-c1-and-c3-epimeric-lesions-of-2-deoxyribonucleosides-in-human-cells/ [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: HEK 293T
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Gelbmann, C.B. and Kalejta, R.F. (2019). The Golgi sorting motifs of human cytomegalovirus UL138 are not required for latency maintenance. Virus Research, [online] 270, p.197646. Available at: https://www.sciencedirect.com/science/article/abs/pii/S0168170219303661 [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: THP-1
Nucleic acid: Plasmid DNA
Application: Gene knockdown
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: THP-1
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Guardiani, C., Fedorenko, O.A., Khovanov, I.A. and Roberts, S.K. (2019). Different roles for aspartates and glutamates for cation permeation in bacterial sodium channels. Biochimica et Biophysica Acta (BBA) - Biomembranes, [online] 1861(2), pp.495–503. Available at: https://www.sciencedirect.com/science/article/pii/S0005273618303493 [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: CHO
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Hu, D., Sun, X., Liao, X., Zhang, X., Zarabi, S., Schimmer, A., Hong, Y., Ford, C., Luo, Y. and Qi, X. (2019). Alpha-synuclein Suppresses Mitochondrial Protease ClpP to Trigger Mitochondrial Oxidative Damage and Neurotoxicity. [online] Acta neuropathologica. Available at: https://pubmed.ncbi.nlm.nih.gov/30877431-alpha-synuclein-suppresses-mitochondrial-protease-clpp-to-trigger-mitochondrial-oxidative-damage-and-neurotoxicity/ [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: SH-SY5Y
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Inoue, T., Abe, C., Kohro, T., Tanaka, S., Huang, L., Yao, J., Zheng, S., Ye, H., Inagi, R., Stornetta, R.L., Rosin, D.L., Nangaku, M., Wada, Y. and Okusa, M.D. (2019). Non-canonical cholinergic anti-inflammatory pathway-mediated activation of peritoneal macrophages induces Hes1 and blocks ischemia/reperfusion injury in the kidney. Kidney International, [online] 95(3), pp.563–576. Available at: https://www.kidney-international.org/article/S0085-2538(18)30773-7/fulltext [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: RAW 264.7
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Janssen, A., Colmenares, S.U., Lee, T. and Karpen, G.H. (2019). Timely Double-Strand Break Repair and Pathway Choice in Pericentromeric Heterochromatin Depend on the Histone Demethylase dKDM4A. [online] Genes & development. Available at: https://pubmed.ncbi.nlm.nih.gov/30578303-timely-double-strand-break-repair-and-pathway-choice-in-pericentromeric-heterochromatin-depend-on-the-histone-demethylase-dkdm4a/ [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: S2
Nucleic acid: Plasmid DNA
Application: CRISPR/Cas9-genome editing
Larson, G.P., Tran, V., Yú, S., Caì, Y., Higgins, C.A., Smith, D.M., Baker, S.F., Radoshitzky, S.R., Kuhn, J.H. and Mehle, A. (2019). EPS8 Facilitates Uncoating of Influenza A Virus. Cell Reports, [online] 29(8), pp.2175–2183.e4. Available at: https://www.sciencedirect.com/science/article/pii/S2211124719313786 [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: HEK 293
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: HEK 293T
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Monderer-Rothkoff, G., Tal, N., Risman, M., Shani, O., Nissim-Rafinia, M., Malki-Feldman, L., Medvedeva, V., Groszer, M., Meshorer, E. and Shifman, S. (2019). AUTS2 isoforms control neuronal differentiation. Molecular Psychiatry, [online] pp.1–16. Available at: https://www.nature.com/articles/s41380-019-0409-1 [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: Neuro-2a
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: HEK 293
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Poles, A., Lucas, G., Green, F., Walser, P., Davey, S., Ridgwell, K. and Wylie, P. (2019). Neonatal Alloimmune Thrombocytopenia Due to a New Alloantigen Bl(a) Defined by an Asp458Gly Substitution in GPIIIa. [online] Transfusion. Available at: https://pubmed.ncbi.nlm.nih.gov/30488955-neonatal-alloimmune-thrombocytopenia-due-to-a-new-alloantigen-bla-defined-by-an-asp458gly-substitution-in-gpiiia/ [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: HEK 293
Nucleic acid: Plasmid DNA
Application: Gene/Protein expression
Prawira, A., Munusamy, P., Yuan, J., Chan, C.H.T., Koh, G.L., Shuen, T.W.H., Hu, J., Yap, Y.S., Tan, M.H., Ang, P. and Lee, A.S.G. (2019). Assessment of PARP4 as a candidate breast cancer susceptibility gene. Breast Cancer Research and Treatment, 177(1), pp.145–153. Available at: https://pubmed.ncbi.nlm.nih.gov/31119570-assessment-of-parp4-as-a-candidate-breast-cancer-susceptibility-gene/[Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: LentiX 293T
Nucleic acid: Lentiviral vectors
Application: Virus production
Runwal, G., Stamatakou, E., Siddiqi, F.H., Puri, C., Zhu, Y. and Rubinsztein, D.C. (2019). LC3-positive structures are prominent in autophagy-deficient cells. Scientific Reports, [online] 9(1), pp.1–14. Available at: https://www.nature.com/articles/s41598-019-46657-z [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: HeLa
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Schmotz, C., Uğurlu, H., Vilen, S., Shrestha, S., Fagerlund, R. and Saksela, K. (2019). MC159 of Molluscum Contagiosum Virus Suppresses Autophagy by Recruiting Cellular SH3BP4 via an SH3 Domain-Mediated Interaction. [online] Journal of virology. Available at: https://pubmed.ncbi.nlm.nih.gov/30842330-mc159-of-molluscum-contagiosum-virus-suppresses-autophagy-by-recruiting-cellular-sh3bp4-via-an-sh3-domain-mediated-interaction/ [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: MCF-7
Nucleic acid: Plasmid DNA
Application: CRISPR/Cas9-genome editing
Singh, A.K., Choudhury, S.R., De, S., Zhang, J., Kissane, S., Dwivedi, V., Ramanathan, P., Petric, M., Orsini, L., Hebenstreit, D. and Brogna, S. (2019). The RNA helicase UPF1 associates with mRNAs co-transcriptionally and is required for the release of mRNAs from gene loci. eLife, [online] 8, p.e41444. Available at: https://elifesciences.org/articles/41444 [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: S2
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Sung, G.-J., Kim, S.-H., Kwak, S., Park, S.-H., Song, J.-H., Jung, J.-H., Kim, H. and Choi, K.-C. (2019). Inhibition of TFEB oligomerization by co-treatment of melatonin with vorinostat promotes the therapeutic sensitivity in glioblastoma and glioma stem cells. Journal of Pineal Research, 66(3), p.e12556. Available at: https://onlinelibrary.wiley.com/doi/abs/10.1111/jpi.12556 [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: HEK 293T
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: A-172
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: U87MG
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Tait, A., Glynne-Jones, P., Hill, A.R., Smart, D.E., Blume, C., Hammarstrom, B., Fisher, A.L., Grossel, M.C., Swindle, E.J., Hill, M. and Davies, D.E. (2019). Engineering multi-layered tissue constructs using acoustic levitation. Scientific Reports, [online] 9(1), pp.1–11. Available at: https://www.nature.com/articles/s41598-019-46201-z [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: 16HBE
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Wang, C.-M., Tsai, S.-C., Lin, J.-C., Wu, Y.-J.J., Wu, J. and Chen, J.-Y. (2019). Association of Genetic Variants of RANK, RANKL, and OPG with Ankylosing Spondylitis Clinical Features in Taiwanese. [online] Mediators of Inflammation. Available at: https://www.hindawi.com/journals/mi/2019/8029863/ [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: hFOB 1.19
Nucleic acid: Plasmid DNA
Application: Gene/protein expression
Zotova, A., Atemasova, A., Pichugin, A., Filatov, A. and Mazurov, D. (2019). Distinct Requirements for HIV-1 Accessory Proteins during Cell Coculture and Cell-Free Infection. Viruses, [online] 11(5). Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563509/ [Accessed 27 Feb. 2020].
Product usage
Product: TransIT®-2020 Transfection Reagent
Cell type: Jurkat
Nucleic acid: Lentiviral vectors
Application: Virus production