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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
170632-47-0
Purity:
≥99%
Formulation:
A crystalline solid
Molecular Formula:
C19H16N2O2
Molecular Weight:
304.3
Alternative Names:
5-[1-(phenyl
Product Description:
YC-1 is an NO-independent activator of soluble guanylyl cyclase. It inhibits collagen (10 µg/ml) and thrombin (0.1 U/ml) induced platelet aggregation with IC50 values of 11.7-14.6 and 57.3-59.3 µM, respectively.{4218,4219} In the absence of NO or CO, 200 µM YC-1 increases the activity of purified soluble guanylyl cyclase 12-fold, with an ED50 value of 20 µM.{4220} At a concentration of 200 µM, YC-1 potentiates the maximal activity of soluble guanylyl cyclase in the presence of NO or CO by 40% and >3,000%, respectively.
