(−)-(α)-Kainic Acid (hydrate)
Catalogue number:
CAY78050-25 mg
Supplier:
Size:
25 mg
Product is available in:
£468.00
Estimated delivery Wed 22 Apr
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
58002-62-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C10H15NO4 • H2O
Molecular Weight:
231.2
Alternative Names:
2s-carboxy-4s-
- MSDS: View or download
Product Description:
A cyclic analog of L-glutamate; binds to GluK1, GluK2, GluK3, GluK4, and GluK5 (Kis = 75.9, 12.7, 32.8, 4.7, and 15 nM, respectively); induces calcium influx and membrane depolarization, as well as glutamate release, in rat brain synaptosomes at 5 mM; induces chromatin condensation and nuclear membrane fragmentation in primary neonatal cerebellar granule neurons at 100 µM; induces convulsive behavior in rats (ED50 = 0.51 nmol/animal) and induces seizures in mice (CD50 = 0.39 nmol/animal); has been commonly used to induce seizures in rodents
