Troglitazone
Catalogue number:
CAY71750-100 mg
Supplier:
Size:
100 mg
Product is available in:
£1112.00
Estimated delivery Wed 7 Jan
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
97322-87-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C24H27NO5S
Molecular Weight:
441.5
Alternative Names:
5-
Product Description:
A selective agonist of PPARγ (EC50s = 0.78 and 0.55 µM for the mouse and human receptors, respectively, in a transactivation assay); selective for PPARγ over PPARα and PPARδ, at which it is inactive at ≤10 µM; exhibits antihyperglycemic and antihyperlipidemic properties in Zucker diabetic fatty rats, reducing plasma glucose and triglyceride levels by 61 and 87% respectively, at 500 mg/kg twice per day; induces cell cycle arrest at the G1 phase in SK-HEP-1 and Hep3B hepatocellular carcinoma cells at 10 µM and increases apoptosis in these cells at ≥30 µM
