Troglitazone
Catalogue number:
CAY71750-100 mg
Supplier:
Size:
100 mg
Product is available in:
£1112.00
Estimated delivery Wed 22 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
97322-87-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C24H27NO5S
Molecular Weight:
441.5
Alternative Names:
5-
Product Description:
A selective agonist of PPARγ (EC50s = 0.78 and 0.55 µM for the mouse and human receptors, respectively, in a transactivation assay); selective for PPARγ over PPARα and PPARδ, at which it is inactive at ≤10 µM; exhibits antihyperglycemic and antihyperlipidemic properties in Zucker diabetic fatty rats, reducing plasma glucose and triglyceride levels by 61 and 87% respectively, at 500 mg/kg twice per day; induces cell cycle arrest at the G1 phase in SK-HEP-1 and Hep3B hepatocellular carcinoma cells at 10 µM and increases apoptosis in these cells at ≥30 µM
