Wy 14643
Catalogue number:
CAY70730-250 mg
Supplier:
Size:
250 mg
Product is available in:
£269.00
Estimated delivery Mon 20 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
50892-23-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C14H14ClN3O2S
Molecular Weight:
323.8
Alternative Names:
2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-acetic acid, nsc 310038, pirinixic acid
Product Description:
An agonist of PPARα; selectively transactivates PPARα over PPARγ in a reporter assay using CV-1 mouse fibroblasts at 100 µM; decreases distal colon protein levels of IFN-γ, TNF-α, IL-1β, and IL-6 in a mouse model of DSS-induced experimental colitis at 2 mg/kg; reduces hepatic triglycerides, leukocyte recruitment, and fibrosis in a mouse model of methionine- and choline-deficient diet-induced steatohepatitis at 0.1% w/w in the diet
