£168.00
Estimated delivery Fri 24 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
491-67-8
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
270.2
Alternative Names:
5,6,7-trihydroxy-2-phenyl-4h-1-benzopyran-4-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
A flavonoid with diverse biological activities; inhibits human 12-LO and 15-LO-1 (IC50s = 0.64 and 1.6 µM, respectively) but is less potent at 15-LO-1 when Triton-X is present (IC50 = 38 µM); inhibits lipid peroxidation (IC50 = 5 µM); inhibits growth of three human hepatocellular carcinoma cell lines (IC50s = 17-70 µg/ml); increases intracellular calcium concentration, ROS accumulation, caspase-9 and -3 activation, and induces apoptosis in ZR-75-1 human breast cancer cells; increases PPARβ/δ levels in microglia; decreases symptoms of EAE in mice at 75 mg/kg per day
Storage Temperature:
-20°C
