N-(2-phenylethyl)-Indomethacin amide
Catalogue number:
CAY70272-50 mg
Supplier:
Size:
50 mg
Product is available in:
£700.00
Estimated delivery Mon 29 Sep
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
261766-32-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C27H25ClN2O3
Molecular Weight:
461
Alternative Names:
n-(2-phenylethyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-acetamide, n-2pia
Product Description:
N-2PIA is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-2PIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.06 and 0.125 µM, respectively.{8243,8513} It is over 400 times less potent as an inhibitor of ovine COX-1.{8513}
