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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
50-78-2
Purity:
≥90%
Formulation:
A crystalline solid
Molecular Weight:
180.2
Alternative Names:
2-(acetyloxy)-benzoic acid, acetylsalicylic acid, nsc 27223, nsc 406186
- Data sheet: View or download
- MSDS: View or download
Product Description:
An NSAID and a COX-1 and COX-2 inhibitor (IC50s = 4.45 and 13.88 µM, respectively, for the human enzymes); an inhibitor of H-PGDS (IC50 = 750 µM for the ovine enzyme); inhibits epinephrine- and ADP-induced platelet aggregation at 6 µg/ml; reduces infarct volume and microglial infiltration in a rat model of ischemia-reperfusion injury induced by MCAO at 30 mg/kg; decreases macrophage infiltration into, increases the number of smooth muscle cells and levels of collagen in, and reduces the area of, atherosclerotic lesions in LDL receptor-deficient mice fed a high-fat diet in the drinking water at 30 mg/L
Storage Temperature:
22°C