Sphingosine-1-phosphate (d18:1)
Catalogue number:
CAY62570-10 mg
Supplier:
Size:
10 mg
Product is available in:
£661.00
Estimated delivery Thu 23 Apr
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
26993-30-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C18H38NO5P
Molecular Weight:
379.5
Alternative Names:
2s-amino-4e-
- MSDS: View or download
Product Description:
A bioactive sphingolipid; an agonist at S1P receptors; increases intracellular calcium levels in TAg-Jurkat cells expressing S1P1 and Gqi5 at 200 nM, as well as in TAg-Jurkat cells expressing S1P2 and S1P3 receptors (EC50s = 8 and 11 nM, respectively); functions as an autocrine or paracrine factor and dysregulation of S1P levels are associated with various disease states, such as inflammation and autoimmunity; involved in cell growth, angiogenesis, immunity, and neuroprotection
