2-Arachidonyl Glycerol ether
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222723-55-9
≥98%
A solution in ethanol
364.6
5z,8z,11z,14z-eicosatetraen-2-glyceryl ether, 2-ag ether, noladin
- Data sheet: View or download
- MSDS: View or download
A potent and selective agonist of CB1 and GPR55 (EC50s = 10, 37, and >30,000 nM for CB1, GPR55, and CB2, respectively); binds to cannabinoid (CB) receptor 1 (Kis = 21.2 and >3,000 nM for CB1 and CB2, respectively, in a radioligand binding assay); displays the typical tetrad of CB activities in mice; more chemically stable than 2-AG with an endogenous half-life of hours rather than minutes; 10-fold less potent than 2-AG in eliciting typical CB1-mediated responses; reduces intraocular pressure in rabbits when administered at doses exceeding 50 µg per eye; increases dietary intake and enhances fat consumption in rats given access to both high-carbohydrate and high-fat diets
-80°C