Tebuconazole
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107534-96-3
≥95%
A solid
C16H22ClN3O
307.8
α-[2-(4-chlorophenyl)ethyl]-α-(1,1-dimethylethyl)-1h-1,2,4-triazole-1-ethanol, bay hwg-1608
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- MSDS: View or download
A triazole fungicide; inhibits 14α-demethylase isolated from U. maydis and S. bicolor (IC50s = 0.05 and 0.16 nM, respectively); inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in a MDA-kb2 assay; reduces testosterone levels and increases testicular levels of progesterone and 17α-hydroxyprogesterone in male rat fetuses following gestational administration (50 and 100 mg/kg per day); gestational and postnatal administration to rats leads to cell death of pyramidal cells in the CA3-4 region of the hippocampus and layer V of the cortex concomitant with impairment in learning in the Morris water maze (20 and 60 mg/kg per day)
