3,5-Dinitrocatechol
Catalogue number:
CAY29180-10 mg
Supplier:
Size:
10 mg
Product is available in:
£236.00
Estimated delivery Wed 3 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
7659-29-2
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C6H4N2O6
Molecular Weight:
200.10584
Alternative Names:
3,5-dinitro-
Product Description:
A potent COMT inhibitor (IC50 = 12 nM); selective for COMT over tyrosine hydroxylase, dopamine β-hydroxylase, dopamine decarboxylase, MAO-A, and MAO-B (IC50s = >14 µM for all); reduces 3-OMD levels in rat serum when administered in combination with L-DOPA and carbidopa compared with control animals receiving only L-DOPA and carbidopa at 30 mg/kg; chronic administration induces COMT-dependent thermal hyperalgesia and increases preference for dark in a light/dark preference test in rats at 15 mg/kg per day for seven days
