XMD8-85
Catalogue number:
CAY29662-10 mg
Supplier:
Size:
10 mg
Product is available in:
£109.00
Estimated delivery Wed 5 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1234479-76-5
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C25H29N7O2
Molecular Weight:
459.54374
Alternative Names:
5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-5,11-dimethyl-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one, erk5-in-1
Product Description:
An ERK5 inhibitor (IC50 = 87 nM in an enzyme assay); selective for ERK5 over TNK2 (IC50 = 959 nM), but does inhibit LRRK2G2019S (IC50 = 26 nM); inhibits EGF-induced ERK5 autophosphorylation in HeLa cells (EC50 = 0.19 µM)
