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XMD8-85

Catalogue number:
CAY29662-10 mg
Supplier:
Size:
10 mg
Product is available in:
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£109.00 Estimated delivery Fri 27 Mar
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1234479-76-5

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C25H29N7O2

Molecular Weight:

459.54374

Alternative Names:

5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-5,11-dimethyl-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one, erk5-in-1

Product Description:

An ERK5 inhibitor (IC50 = 87 nM in an enzyme assay); selective for ERK5 over TNK2 (IC50 = 959 nM), but does inhibit LRRK2G2019S (IC50 = 26 nM); inhibits EGF-induced ERK5 autophosphorylation in HeLa cells (EC50 = 0.19 µM)

CAY29662-10 mg: XMD8-85
CAY29662-10 mg: XMD8-85