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ADH-1

Catalogue number:
CAY29981-25 mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£675.00 Estimated delivery Tue 16 Dec
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CAS Number:

229971-81-7

Purity:

≥98%

Molecular Weight:

570.68768

Alternative Names:

n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-l-cysteinamide, cyclic (1→5)-disulfide, n-ac-chavc-nh2

Product Description:

A cyclic peptide antagonist of N-cadherin; inhibits neurite outgrowth in cerebellar neurons cultured on N-cadherin-expressing 3T3 cell monolayers (IC50 = 0.323 mM); inhibits cell scattering and motility induced by collagen I in Capan-1 cells and wild-type and N-cadherin-overexpressing BxPC-3 cells at 0.2 mg/ml; induces apoptosis in N-cadherin-overexpressing, but not knockdown, BxPC-3 at 1 mg/ml; reduces tumor growth in an N-cadherin-overexpressing BxPC-3 mouse xenograft model at 50 mg/kg

CAY29981-25 mg: ADH-1
CAY29981-25 mg: ADH-1