p,p'-DDE
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72-55-9
≥98%
A solid
C14H8Cl4
318.02412
1,1'-(2,2-di
A metabolite and degradation product of the pesticide DDT; accumulates in various fish and sediment surrounding a DDT manufacturing plant; inhibits estrogen binding to rtERs (IC50 = 8 µM); induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles; induces concentration-dependent secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles; decreases ATP levels, the proportion of sperm with high mitochondrial membrane potential, and motility of human sperm in vitro from 50-100 µM




