AZ 12216052
Catalogue number:
CAY29460-25 mg
Supplier:
Size:
25 mg
Product is available in:
£522.00
Estimated delivery Wed 17 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1290628-31-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C19H22BrNOS
Molecular Weight:
392.35412
Alternative Names:
2-[[(4-bromo
Product Description:
A positive allosteric modulator of mGluR8; potentiates glutamate-induced [35S]GTPγS binding in GHEK cells expressing human mGluR8b (EC50 = 1 µM); inhibits MPP+-induced decreases in the viability of undifferentiated SH-SY5Y cells at 0.001-1 µM and in retinoic acid-differentiated SH-SY5Y cells at 0.1 and 1 µM; increases the time spent in the open areas of the elevated zero maze and reduces the acoustic startle response, avoidable and unavoidable anxiogenic stimuli, respectively, in mice at 10 mg/kg
