RJR 2429 (hydrochloride)
Catalogue number:
CAY29745-10 mg
Supplier:
Size:
10 mg
Product is available in:
£257.00
Estimated delivery Mon 12 Jan
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1021418-53-0
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C12H16N2 • 2HCl
Molecular Weight:
261.1902
Alternative Names:
2-(3-pyridi
Product Description:
An agonist of nicotinic AChRs; selective for α4β2 or α7 subunit-containing nicotinic AChRs (Kis = 0.7 and 10.9 nM in isolated rat cortex and isolated rat hippocampus, respectively) over α1βɣδ subunit-containing nicotinic AChRs (EC50 = 1,000 nM in PC12 cells); induces dopamine release from isolated rat striatal synaptosomes (EC50 = 2.4 nM) and increases nicotine-induced elevations in epinephrine and norepinephrine levels in isolated rat adrenal gland at 100 µM; inhibits nicotine-induced ion flux in isolated rat thalamic synaptosomes (IC50 = 154 nM)
