RJR 2429 (hydrochloride)
Catalogue number:
CAY29745-10 mg
Supplier:
Size:
10 mg
Product is available in:
£257.00
Estimated delivery Wed 8 Jul
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1021418-53-0
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C12H16N2 • 2HCl
Molecular Weight:
261.1902
Alternative Names:
2-(3-pyridi
Product Description:
An agonist of nicotinic AChRs; selective for α4β2 or α7 subunit-containing nicotinic AChRs (Kis = 0.7 and 10.9 nM in isolated rat cortex and isolated rat hippocampus, respectively) over α1βɣδ subunit-containing nicotinic AChRs (EC50 = 1,000 nM in PC12 cells); induces dopamine release from isolated rat striatal synaptosomes (EC50 = 2.4 nM) and increases nicotine-induced elevations in epinephrine and norepinephrine levels in isolated rat adrenal gland at 100 µM; inhibits nicotine-induced ion flux in isolated rat thalamic synaptosomes (IC50 = 154 nM)
